Description

URL

https://www.ajp.eg.net/article.asp?issn=1687-9945;year=2020;volume=33;issue=3;spage=107;epage=116;aulast=Taha;type=3

DOI

https://www.ajp.eg.net/article.asp?issn=1687-9945;year=2020;volume=33;issue=3;spage=107;epage=116;aulast=Taha;type=3

Brief

Neonates in NS group had significantly higher CRP, as well as hepcidin and presepsin serum levels versus control. Hepcidin and presepsin were significantly higher among nonsurvivors versus survivors and in neonates with neurological deficits versus neonates without neurological deficit. Sensitivity and specificity were 88.33 and 82.50%, respectively, for CRP; 93.33 and 90.00%, respectively, for hepcidin; and 91.67 and 90.00%, respectively, for presepsin. Of NS group, 66.7% had late-onset sepsis, 20.0% had neurological deficits, and 45.0% were survivors. Among survivors, the most frequent findings in EEG were focal epileptic discharge (57.4%) followed by continuous normal voltage (46.3%), and generalized periodic discharge with triphasic waves (42.6%), whereas in CT, the most frequent findings were mild hypoxia (37.0%) followed by periventricular hypoxia (33.3%). Conclusions Hepcidin and presepsin have an important role in prediction and diagnosis of N

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